Eukaryotic chromosomes replicate from multiple discrete loci termed origins of replication. These sites are first recognised by the origin recognition complex (ORC), which, together with Cdc6 and Cdt1 ...

From the Bedalov Lab, Translational Science and Therapeutics and Human Biology Divisions When I asked Foss and Bedalov whether the known replication origins in yeast shared any sequence-level features ...

Archaeal DNA replication combines features of bacterial and eukaryotic systems within a unique framework adapted to extreme environments and diverse genome architectures. Initiation typically occurs ...

If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and the middle. Is everything packed? What time should we leave? Will there be ...