Cells carry their own growth switches. When enough nutrients—amino acids in particular—are available, cells flip this switch ...

In many animal tissues, stem cells continually divide to create new cells that replace old or damaged ones. However, this ...

Phosphoinositides are a family of membrane lipids distinguished by phosphate groups at specific positions on the inositol ring, acting as spatial and temporal organisers of cell activity. Through ...

Illustration of small molecule modulation of β-arrestins and GPCR signaling pathways based on concepts developed by the Lefkowitz Laboratory, Duke University. To function normally, nearly every cell ...